做爱影片

（1）生物大分子自组装及其高分子物理化学特性研究

将高分子物理原理应用于生物材料科学，聚焦于揭示生物大分子材料的多尺度、动态组装过程，致力于发展结构化和功能化的生物大分子自组装材料。

（2）凝聚体形成机制研究及其物理化学性质的精准调控

旨在揭示驱动凝聚体形成的关键驱动力及影响因素。通过结合多种材料表征技术，探索序列与凝聚体物理化学性质之间的关联，实现对凝聚行为的精准调控。

（3）基于分子动力学模拟解析分子水平的自组装机制

采用全原子分子动力学模拟系统研究自组装过程的分子机制；同时结合深度学习方法，构建预测模型，实现从生物大分子序列与分子间相互作用到相分离行为的映射，为新型功能性凝聚体的设计提供理论基础。

课题组长期聚焦于高分子物理化学于生物材料的交叉领域，专注于生物大分子材料的自组装结构以及功能特性的研究，致力于将高分子物理原理与材料科学应用相结合。近年来多肽材料设计与自组装、液液相分离行为分析、仿生粘附材料等方向取得进展。研究成果以第一/通讯作者在Science、Nature Nanotechnology、Science Advances、Nature Communications、JACS等高级高水平期刊发表。曾获新加坡国家科学研究基金会会士（2019年），新加坡南洋理工大学南洋讲席助理教授（2019年），Springer博士论文奖（2013年）等多项荣誉奖励，入选长江学者奖励计划。本课题组长期招收具有理论计算、生物、材料等相关专业和科研背景的本科生、研究生和博士后研究者，热情欢迎对上述研究领域感兴趣并有志于长期从事科学研究或创新创业工作的同学加入我们的团队！

概况

在Science, Nature Nanotechnology, Science Advances, Nature Communications, Journal of the American Chemical Society等国际顶级期刊以及生物材料科学领域的重要期刊上发表了80篇以上的研究论文。这些期刊论文的引用量超过6900次（H指数=36）（来源于谷歌学术，截至2025年4月）。

主要论文列表 (* 表示通讯作者)

16. Shujun Chen, Guijin Zou, Qi Guo, Xuliang Qian, Haopeng Li, Huajian Gao*, and Jing Yu*. Extreme pH Tolerance in Peptide Coacervates Mediated by Multivalent Hydrogen Bonds for Enzyme-Triggered Oral Drug Delivery. Journal of the American Chemical Society, 2025, 147(11), 9704-9715.

15. Yusai Zhou, Rong Chang, Zhenyue Yang, Qi Guo, Mengyao Wang, Bo Jia, Bo Li, Bodan Deng, Yubin Ren, Huaxia Zhu, Xinyan Wang, Qinrui Wang, Han Wen, Hongjie Zhang, Jing Yu*, Yong-Xiang Chen*, and Kai Liu*. Dynamic peptide nanoframework-guided protein coassembly: advancing adhesion performance with hierarchical structure. Journal of the American Chemical Society, 2025, 147(3), 2335-2349.

14. Jiazheng Lao, Yang Jiao, Yingchao Zhang, Hanyan Xu, Yutong Wang, Yinji Ma*, Xue Feng*, and Jing Yu*. Intrinsically adhesive and conductive hydrogel bridging the bioelectronic-tissue interface for biopotentials recording. ACS Nano, 2025, 19(8), 7755-7766.

13. Georgina E. K. K. Seah, Zhi Yuan Lee, Ai Wei Gan, Xin Jiang, Sirin Kamarulzaman, Jing Yu*, and Shermin S. Goh*. Covalent adaptable networks for sustainable soft electronic sensors and actuators. Advanced Functional Materials, 2025, 35, 2421060.

12. Xiaoxiang Wen, Jinxia Zhang, Jianing Li, Yue Li, Yuchen Shi, Xuegang Lu*, Sen Yang*, and Jing Yu*. Bio-inspired cholesteric phase cellulose composite with thermochromic and circularly polarized structural color for multilevel encryption. Advanced Functional Materials, 2024, 34(2), 2308973.

11. Yue Sun, Xi Wu, Jianguo Li, Milad Radiom, Raffaele Mezzenga, Chandra Shekhar Verma, Jing Yu, and Ali Miserez*. Phase-separating peptide coacervates with programmable material properties for universal intracellular delivery of macromolecules. Nature Communications, 2024, 15(1), 10094.

10. Haopeng Li, Xuliang Qian, Harini Mohanram, Xiao Han, Huitang Qi, Guijin Zou, Fenghou Yuan, Ali Miserez, Tian Liu*, Qing Yang*, Huajian Gao*, and Jing Yu*. Self-assembly of peptide nanocapsules by a solvent concentration gradient. Nature Nanotechnology, 2024, 19(8), 1141-1149.

9. Ali Miserez*, Jing Yu*, and Pezhman Mohammadi*. Protein-based biological materials: Molecular design and artificial production. Chemical Reviews, 2023, 123(5), 2049-2111.

8. Lei Ge†, Hanyan Xu†, Xin Jiang, and Jing Yu*. Oligopeptide self-assembly: mechanisms, stimuli-responsiveness, and biomedical applications. CCS Chemistry, 2023, 6(1), 69-90.

7. Yingchao Zhang, Yurong Tan, Jiazheng Lao, Huajian Gao, and Jing Yu*. Hydrogels for flexible electronics. ACS Nano, 2023, 17(11), 9681-93.

6. Qi Guo, Guijin Zou, Xuliang Qian, Shujun Chen, Huajian Gao*, and Jing Yu*. Hydrogen-bonds mediate liquid-liquid phase separation of mussel derived adhesive peptides. Nature Communications, 2022, 13(1), 5771.

5. Kanagavel Deepankumar, Qi Guo, Harini Mohanram, Jessica Lim, Yuguang Mu, Konstantin Pervushin, Jing Yu*, and Ali Miserez*. Liquid-liquid phase separation of the green mussel adhesive protein pvfp-5 is regulated by the post-translated dopa amino acid. Advanced Materials, 2022, 34(25), 2103828.

4. Shujun Chen, Qi Guo, and Jing Yu*. Bio-inspired functional coacervates. Aggregate, 2022, 3(6), e293.

3. Fanfan Fu, Jilei Wang, Hongbo Zeng*, and Jing Yu*. Functional conductive hydrogels for bioelectronics. ACS Materials Letters, 2020, 2(10), 1287-1301.

2. J. Yu†, N. E. Jackson†, X. Xu, Y. Morgenstern, Y. Kaufman, M. Ruths, J. J. de Pablo*, and M. Tirrell*. Multivalent counterions diminish the lubricity of polyelectrolyte brushes. Science, 2018, 360(6396), 1434-1438.

1. Jing Yu†, Nicholas E. Jackson†, Xin Xu, Blair K. Brettmann*, Marina Ruths, Juan J. de Pablo, and Matthew Tirrell. Multivalent ions induce lateral structural inhomogeneities in polyelectrolyte brushes. Science Advances, 2017, 3(12), eaao1497.

书籍与章节：

1. Yu J. (2014). Adhesive Interactions of Mussel Foot Proteins (Springer Theses). Springer. 2014. ISBN-10: 3319060309 | ISBN-13: 978-3319060309.

2. Greene G.W., Lee D., Yu J., Das S., Banquy X., and Israelachvili J.N. (2013). Lubrication and Wear Protection of Natural (Bio) Systems. In: Zeng H. (eds) Polymer Adhesion, Friction, and Lubrication, John Wiley & Sons. 2013. ISBN: 978-0-470-91627-8.